Benefits of GLP-1 drugs for weight loss on key clinical markers, alongside the risks of elevated blood glucose, insulin resistance and obesity

Brain

Appetite, food intake

Stroke

Mental health

Neurodegeneration

Respiratory

Improved asthma control

Infection susceptibility

Cardiovascular system

Adverse cardiovascular events

Blood pressure

Cardiovascular disease

Stomach

Gastric emptying

Obesity

Nerve damage
(Peripheral neuropathy)

Chronic inflammation

Musculoskeletal ailments

Kidney

Increases filtration rate

Kidney disease

Liver

Insulin sensitivity

Fat content

Liver disease

Pancreas

Insulin secretion

Type 2 diabetes

Circulation

Triglycerides

Cholesterol

HbA1c

Fasting insulin and glucose

Eye damage (retinopathy)

Cancer

 Benefits of GLP-1 drugs for weight loss​ 

 Elevated disease risks of obesity​

Source: Swiss Re